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According to Frank Shallenberger, M.D (1) Bio-oxidatives - H2O2 and Ozone (The saturated oxygen in our cream) works because -

1. They stimulate the production of white blood cells, which are necessary to fight infection.

2. Bio-oxidatives are anti-fungal.

3. They increase oxygen and hemoglobin disassociation, thus increasing the delivery of oxygen from the blood to the cells.

4. They increase red blood cell membrane distensibility, thus enhancing their flexibility and effectiveness.

5. Bio-oxidatives increase tissue oxygenation, thus bringing about patient improvement.

H2O2 (a bio-oxidative) is involved in all of life's vital processes, and must be present for the immune system to function properly. The cells in the body that fight infection (known as granulocytes) produce H2O2 as a first line of defense against invading organisms like parasites, viruses, bacteria and fungi. Some of the biological killing activity of H2O2 can be attributed to gamma interferon. Production of gamma interferon by human natural killer cells and monocytes, is stimulated by H2O2 (2).

H2O2 appears to be involved in many intermediate biochemical pathways. Additionally, it appears to kill certain bacteria, parasites, yeast, protozoa, inhibit viruses, and oxidize immunocomplexes. T. Ramasarma (3)

IF THAT WASNT ENOUGH WE ADDED MANUKA OIL...

Manuka oil has shown effectiveness in laboratory tests against 39 separate micro-organisms(4) (Including - Candida albicans - responsible for Thrush and Yeast Infections).

Perhaps most interesting with the current emergence of strains of antibiotic-resistant organisms is that laboratory tests have indicated Manuka oils effectiveness as a treatment against some antibiotic-resistant organisms. Up to 30% of strains of Thrush and Yeast Infections are resistant to over the counter medication.

The oil has been tested against 39 separate micro-organisms and has been found active against all of them. A list of some of these follows with the MIC (Minimum Inhibitory Concentration) for each. MIC of oil is the lowest concentration that will inhibit the growth of a specified micro-organism. At the bottom is Candida Albicans which causes Thrush and Yeast Infections.

Gram Positive Bacteria MIC

Staphylococcus  aureas 0.039
Staphylococcus  aureas methacillin resistant 0.0195 
Staphylococcus epidermidis 0.078 
Streptococcus  faecalis 0.039 
Streptococcus agalactiae 0.039 
Micrococcus luteus 0.0195 
Sarcina  lutea 0.078 
Bacillus subtilis 0.156 
Listeria monocytogenes 0.039
 
Gram Negative  Bacteria %
 
Escherichia coli 2.5 
Pseudomonas aeruginosa 997 2.5 
Klebsiella pneumoniae  5 
Proteus vulgaris 5 
Vibrio furnissii 0.625 
Pseudomonas aeruginosa 2584 >5 
Pseudomonas  fluorscens 5 

Fungi % 

Trichophyton mentagrophytes 0.078 
Trichophyton rubrum <0.039  
Microsporum canis <0.039 
Aspergillus niger >1.25 
CANDIDA ALBICANS  0.625   

1. Frank, "Intravenous Ozone Therapy in HIV-related Disease" Proceedings: Fourth International Bio-Oxidative Medicine Conference, April 1993.

2. Archibald FS and Duong MN: Superoxide Dismutase and Oxygen Toxicity Defenses in the Genus Neisseria. Infect Immun 1986; 51(2): 631-41

3. Mallams JT, Finney JW, and Balla GA: The Use of Hydrogen Peroxide As A Source of Oxygen in A Regional Intra-Arterial Infusion System. So M J 1962; 55: 230-232

4. Cooke A, Cooke MD, Cawthron Institute, An investigation into the Antimicrobial Properties of Manuka and Kanuka Oil, February 1991